I'm a program-specific researcher (post doc) at ASHBi, KUIAS, Kyoto University in Seirin-Lee's lab.

My expertise is to apply math and computer science to real biology.

I studied mathematics at TU Kaiserslautern with stays at TU Delft and The University of Auckland, and obtained my PhD at University of Vienna in Sara Merino-Aceituno's group.

You can find a description of my current projects in the research section, talk and activities here and more info in my CV.

News and Blog

September 2024: New Nature Communications publications on EMT and gastrulation are out!

March 2024: Our standalone EMT simulator[1] is online semtor.github.io! 🎉

Newest blog entries: 🦙 How to chat with LLama3; 📑 Spellchecking in LaTeX with Grammarly; 🎨 MyPaintEdSlides; 🍎 Interactive modelling with p5.js;

📧 plunder.steffen.2a@kyoto-u.ac.jp

🔗 GitHub/SteffenPL | Google Scholar | ORCID | ResearchGate | LinkedIn | Twitter/X

Preprints

  1. M. Mira Osuna, S. Plunder, E. Theveneau, Roland Le Borgne, The directionality of collective cell delamination is governed by tissue architecture and cell adhesion in a Drosophila carcinoma model. (2024) bioRxiv.

  2. S. Merino-Aceituno, S. Plunder, C. Wytrzens, H. Yoldaş, Macroscopic effects of an anisotropic Gaussian-type repulsive potential: nematic alignment and spatial effects. (2024) arxiv.

  3. S. Plunder, S. Merino-Aceituno, Convergence proof for first-order position-based dynamics: An efficient scheme for inequality constrained ODEs. (2023) arxiv.

Publications (peer-reviewed)

  1. H. Jäger, É. Grosjean, S. Plunder, C. Redenbach, A. Keilmann, B. Simeon, C. Surulescu Cell seeding dynamics in a porous scaffold material designed for meniscus tissue regeneration. Proceedings in Applied Mathematics & Mechanics (2024) DOI: 10.1002/pamm.202400133.

  2. E. Despin-Guitard, V. S. Rosa, S. Plunder, N. Mathiah, K. Van Schoor, E. Nehme, S. Merino-Aceituno, J. Egea, M. N. Shahbazi, E. Theveneau & I. Migeotte Non-apical mitoses contribute to cell delamination during mouse gastrulation. Nature Communications (2024) DOI:10.1038/s41467-024-51638-6.

  3. S. Plunder, C. Danesin, B. Glise, M. A. Ferreira, S. Merino-Aceituno, E. Theveneau, Modelling variability and heterogeneity of EMT scenarios highlights nuclear positioning and protrusions as main drivers of extrusion. Nature Communications (2024) DOI:10.1038/s41467-024-51372-z.

  4. S. Plunder, M. Burkard, T, Helling, U. M. Lauer, L. E. Hoelzle, L. Marongiu, Determination of optimal phage load and administration time for antibacterial treatment. Current Protocols (2024) DOI:10.1002/cpz1.954.

  5. S. Plunder, B. Simeon, The mean-field limit for particle systems with uniform full-rank constraints. Kinetic and Related Models (2023) DOI:10.3934/krm.2023012, arxiv.

  6. S. Plunder, M. Burkard, U. Lauer, S. Venturelli, L. Marongiu, Determination of phage load and administration time in simulated occurrences of antibacterial treatments. Frontiers of Medicine (2022) DOI: 10.3389/fmed.2022.1040457.

  7. S. Plunder, B. Simeon, Coupled Systems of Linear Differential-Algebraic and Kinetic Equations with Application to the Mathematical Modelling of Muscle Tissue. In: Reis, T., Grundel, S., Schöps, S. (eds) Progress in Differential-Algebraic Equations II. Differential-Algebraic Equations Forum. Springer (2020) DOI: 10.1007/978-3-030-53905-4_12, arxiv.

Software packages

I am currently making various tools for agent-based modelling available as Julia packages.

  • SpatialHashTables.jl: A Julia package for spatial hashing of particles (in 2D and 3D). This allows fast collision detection even is unbounded domains.
  • BoundedDegreeGraphs.jl: A Julia package for graphs with bounded degree, with focus on allocation free operations commonly used in agent-based modelling.

  1. EMT stands for epithelial-to-mesenchymal transitions, a process responsible for good things like neural crest formation and wound healing, but also bad thinks like cancer and fibrosis. ↩︎