SimulationApical side (red)
Simulation
end: Click to restart simulation.
Basal side (black)
Time = 10
0h 12h 24h 36h 48h
ABS
Parameters
(Restart required)
Number of experimental cells
0111
Number of cells undergoing EMT-like events.
11 (heterogeneous) EMT cells
Number of cells undergoing EMT. Disable heterogeneity to
enable the selection of zero or one EMT cells.
Interkinetic nuclear movements
none100%
Determines probability that nuclei of experimental cells perform pre-mitosis rapid apical movement
(PRAM).
Interkinetic nuclear movements
Determines if nuclei of experimental cells perform pre-mitosis rapid apical movement (PRAM).
EMT: Protrusions
none100%
Determines probability that the basal point of experimental cells display a seek-and-grab behavior
(P).
This can only occur if the EMT scenario includes B (loss of
basal adhesion).
EMT: Protrusions
Determines if the basal point of experimental cells display a seek-and-grab behavior (P).
This can only occur if the EMT scenario includes B (loss of
basal adhesion).
Heterogeneity
If checked, each experimental cell randomly picks an EMT-like scenario.
Then users can set the probability of INM and Protrusions to 0, 50 or 100%.
Determines which EMT-like scenario experimental cells will perform.
EMT scenario
Random EMT scenario per cell
For heterogeneous EMT, each cell selects randomly if A, B, S are occuring.
Disable heterogeneity to select a specific EMT scenario.